Titanium alloys are widely used in various industries due to their excellent mechanical properties, corrosion resistance, and biocompatibility. However, the welding of titanium alloys poses challenges due to their high reactivity with oxygen and nitrogen, which can lead to the formation of brittle intermetallic compounds and porosity in the weld zone. The selection of appropriate TIG welding parameters is crucial to ensure the desired microstructure and mechanical properties in the welded joints. Therefore, there is a need for a comprehensive review of the effects of TIG welding parameters on the microstructure and mechanical properties of titanium alloys to provide guidelines for optimizing welding processes. The research methodology involved a systematic review of existing studies on TIG welding of titanium alloys. The research methodology involved a literature search of existing studies on TIG welding of titanium alloys using online databases. The selected studies were analyzed to identify the effects of welding parameters such as welding current, welding speed, and shielding gas flow rate on the microstructure and mechanical properties of titanium alloys. The analysis of the literature revealed that the selection of TIG welding parameters significantly influences the microstructure and mechanical properties of titanium alloys. Higher welding currents and slower welding speeds were found to increase the heat input, leading to larger grain sizes and reduced mechanical properties in the weld zone. On the other hand, lower welding currents and higher welding speeds resulted in finer microstructures and improved mechanical properties. Additionally, the use of appropriate shielding gas flow rates was found to minimize the formation of porosity and intermetallic compounds in the weld zone. The study provides valuable insights into the optimization of TIG welding processes parameters to achieve desired properties in the welded joints. Welding parameters should be selected carefully in order to control the heat input and minimize the formation of defects in the weld zone. Future research should focus on developing advanced welding techniques and process monitoring systems to further improve the quality of welded titanium alloys.